The demand for vaccines is growing rapidly as the US grapples with a record death rate from Covid-19 and the threat of new, more contagious variants. After a slow start in December, many states and cities have rapidly accelerated vaccine delivery, expanded access to larger populations, and established mass testing sites.
But now there’s a new wrinkle: some mayors and governors say they have run out of available vaccines and have had to cancel appointments.
Biden’s government has promised to revise the country’s volatile vaccination efforts, but there is only so much it can do to increase the supply available.
Here’s what you need to know:
How many cans are available?
There are simply not enough doses of approved vaccines to meet the huge demand. And that probably won’t change in the next few months.
The two approved vaccine companies, Moderna and Pfizer, each have promised to make 100 million doses of vaccine available to the United States by the end of March, or enough to give 100 million people the two needed vaccinations.
But that doesn’t mean that these 200 million cans are lying in a factory warehouse somewhere waiting to be shipped. Both companies are making the cans at full capacity and collectively release about 12 million cans per week, a number that is expected to increase gradually.
From Wednesday, almost 36 million cans the Pfizer and Moderna vaccines had been distributed to state and local governments. However, only about 16.5 million shots were given to patients.
However, if the local health authorities are better able to handle the distribution of vaccines, they will ultimately catch up with the limited supply. Some local officials, including those in New York City, said they had reached this point and had to cancel appointments because they said they didn’t have enough.
President Biden said he would use the Defense Production Act to increase supply. Will that help?
Vaccine experts and the companies themselves have stated that applying the Defense Production Act will not significantly increase supply, at least in the short term, although any little bit could help. This is because the production facilities are already at full or near-full capacity and there is a global race to develop vaccines that use a limited amount of resources.
Although the Trump administration has been criticized for not using the Defense Production Act more aggressively to stimulate production of test supplies and protective equipment, it has done so did Use the act many times to Give priority access to vaccine manufacturers to suppliers of raw materials and equipment.
In one Plan published on ThursdayBiden’s government said it would continue to use the law to increase supplies needed to make vaccines, as well as other materials needed to immunize tens of millions of people. Although the plan was few in detail, an example is given of increasing the production of a special syringe that can squeeze six cans from Pfizer vials that were originally supposed to contain five.
What about the federal vaccine supply?
There are no vaccine reserves to speak of. For the most part, vaccines are shipped every week when they are made. (The exception is a small emergency supply that the Biden government has announced will continue.)
Last week, Alex M. Azar II, the outgoing Secretary for Health and Human Services, Caused confusion when he announced that the federal government would release a reserve of vaccine doses. Many states have been told that an influx of vaccines is on the way that will allow more people to be vaccinated.
In his press conference, Mr Azar urged states to open their vaccination guidelines, saying they moved too slowly to use the doses they had already received. As a result, several governors, including Andrew Cuomo of New York, changed admissions rules to allow people 65 and over to get the vaccine.
While the exact order of vaccine recipients may vary from state to state, most doctors and residents of long-term care facilities will come first. If you want to understand how this decision is made, This article will help.
Life will only get back to normal once society as a whole receives adequate protection against the coronavirus. Once countries approve a vaccine, they can only vaccinate a few percent of their citizens in the first few months. The unvaccinated majority remain susceptible to infection. A growing number of coronavirus vaccines show robust protection against disease. However, it is also possible for people to spread the virus without knowing they are infected because they have mild or no symptoms. Scientists don’t yet know whether the vaccines will also block the transmission of the coronavirus. Even vaccinated people have to wear masks for the time being, avoid the crowds indoors and so on. Once enough people are vaccinated, it becomes very difficult for the coronavirus to find people at risk to become infected. Depending on how quickly we as a society achieve this goal, life could approach a normal state in autumn 2021.
Yeah, but not forever. The two vaccines that may be approved this month clearly protect people from contracting Covid-19. However, the clinical trials that produced these results were not designed to determine whether vaccinated people could still spread the coronavirus without developing symptoms. That remains a possibility. We know that people who are naturally infected with the coronavirus can spread it while they don’t have a cough or other symptoms. Researchers will study this question intensively when the vaccines are introduced. In the meantime, self-vaccinated people need to think of themselves as potential spreaders.
The vaccine against Pfizer and BioNTech, like other typical vaccines, is delivered as a shot in the arm. The injection is no different from the ones you received before. Tens of thousands of people have already received the vaccines, and none of them have reported serious health problems. However, some of them have experienced short-lived symptoms, including pain and flu-like symptoms that usually last a day. It is possible that after the second shot, people will need to have a day off to work freely or go to school. While these experiences are not pleasant, they are a good sign: they are the result of your own immune system’s encounter with the vaccine and a strong reaction that ensures lasting immunity.
No. Moderna and Pfizer vaccines use a genetic molecule to boost the immune system. This molecule, known as mRNA, is eventually destroyed by the body. The mRNA is packaged in an oily bubble that can fuse with a cell, allowing the molecule to slide inside. The cell uses the mRNA to make proteins from the coronavirus that can stimulate the immune system. At any given moment, each of our cells can contain hundreds of thousands of mRNA molecules that they produce to make their own proteins. As soon as these proteins are made, our cells use special enzymes to break down the mRNA. The mRNA molecules that our cells make can only survive a few minutes. The mRNA in vaccines is engineered to withstand the cell’s enzymes a little longer, so the cells can make extra viral proteins and trigger a stronger immune response. However, the mRNA can hold for a few days at most before it is destroyed.
However, last Friday, senior administrative officials made it clear that all of these reserve doses were already intended to be used as booster shots for those who had received the vaccine and that Mr Azar was just the logical extension a distribution policy That was set by high-ranking federal officials in December when deliveries began. The release of the reserve doses would go to people who needed their second dose, not new groups of people who received their first shot.
In the future, Azar said, the government will switch to a new model: instead of sticking to a reserve of booster shots, every weekly shipment from the manufacturers would include doses for new people as well as second doses for those due for their booster shots. President Biden repeated this policy when he announced his vaccination schedule last week.
Will there be enough vaccines to give everyone a second dose?
Federal officials previously said they worked with states to find out who received a vaccine and when they were due for their booster shots, three weeks later for the Pfizer vaccine, and four weeks later for the Moderna vaccine.
They said that each weekly delivery gives priority to people who need their second dose that week, and what is left is used to vaccinate new people.
However, the plan relies on federal and state governments working together to specify exactly who has received a vaccine and what is needed from week to week. Many state governments have complained that they do not have the resources to carry out the vaccine distribution plan and the next few weeks will show how well the system works.
Biden’s new administration has vowed to revise the distribution to the states to give local officials more transparency on how much vaccine to expect in hopes of allowing states to better plan.
Some Democratic governors have asked to buy vaccines directly from Pfizer. Is that possible?
No, that probably won’t happen.
Last week, Michigan Governor Gretchen Whitmer did asked the federal government for permission to purchase 100,000 doses of vaccine directly from Pfizer. And on Monday, Governor Cuomo wrote a letter to Pfizer Ask the state to buy vaccines directly.
Pfizer and Moderna supplies have been fully drawn for at least the first quarter of this year, meaning a replacement vaccine is unlikely to be sold to individual states.
Additionally, the emergency approvals for the Pfizer and Moderna vaccines provide for the federal government to oversee distribution.
In a statement, a Pfizer spokeswoman said the company was “open to working with the US Department of Health on a distribution model that will allow as many Americans as possible to get access to our vaccine as soon as possible.” However, she noted, “Before we can even think about selling direct to state governments, H.H.S. would have to approve this proposal. “
A state official said Tuesday that the governor felt it was important to exhaust all of his options, no matter how improbable, and pointed to his efforts in March to buy fans direct from manufacturers – which sparked a bidding war between states he later criticized the federal government to refuel.
However, advisors to the Biden government have indicated that they are not in favor of such a move. On Monday, Dr. Celine Gounder, a pandemic advisor to Mr Biden during his change of presidency, said that if states could do separate deals, it would cause more problems than it would solve.
In an interview on CNBC, Dr. Gounder’s earlier criticism from Mr. Cuomo for bidding on ventilators. “I think this kind of approach to vaccine allocation will frankly lead to the same situation that he himself criticized last spring,” she said said.
Are we going to get more vaccines soon?
Yes, most likely.
At least three other vaccines are in late-stage clinical trials, and the success of any one of those vaccines could mean millions more doses for US citizens by spring.
Johnson & Johnson is expected to announce the results of its vaccine study every day. If this is successful, the first doses could be available in the US by February. Although early production of the vaccine has lagged, the company has signed a contract to deliver 100 million doses of its single-dose vaccine by the end of June.
Results of studies with two-dose vaccines from AstraZeneca and Novavax could also be published by March and April. AstraZeneca has an agreement with the US government to supply 300 million doses and Novavax to supply 110 million doses.
Additionally, both Pfizer and Moderna state that their factories are adding and expanding capacity every week. They have signed contracts to deliver an additional 100 million doses of their vaccines each during the second quarter of this year.
When will we have enough vaccines for everyone in the country?
It is still not clear, albeit conservatively, that there could be enough vaccines by the summer.
With no other vaccines approved, the United States has signed contracts with Pfizer and Moderna for a total of 400 million doses to be dispensed by the summer, or enough for 200 million people.
That’s pretty close to the American population of 260 million adults (the vaccines aren’t yet approved for children, although studies are ongoing).
But if other vaccines prove safe and effective – which experts believe is likely – millions of people could be vaccinated faster, possibly by late spring.